CBD Oil | Drops, Sprays, Capsules & Balms
CBD Oil is one of the most researched therapeutic substances in the world. Explore the many possible benefits of this exciting healing potential of this hemp derived product.
What Is CBD?
CBD is one of over 60 compounds found in cannabis that belong to a class of ingredients called cannabinoids. Until recently, THC (tetrahydrocannabinol) was getting most of the attention because it’s the ingredient in cannabis that produces mind-altering effects in users, but CBD is also present in high concentrations — and the medical world is realizing that its list of medical benefits continues to grow.
CBD is the major nonpsychoactive component of Cannabis sativa. According to a 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits including acting in some experimental models as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent, and is therefore a potential medicine for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety and schizophrenia. (1)
Research is beginning to show that CBD is different than other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. CB1 receptors are widely distributed, but are particularly abundant in areas of the brain, including those concerned with movement, coordination, pain and sensory perception, emotion, memory, cognition, autonomic and endocrine functions. (2)
CB2 receptors are found mostly in the immune system, and they seem to reduce inflammation and certain kinds of pain. Although cannabinoids all have similar structures, they display a wide array of actions at each of the different receptors.
However, scientists are finding out that CBD has very little effect on CB1 and CB2 receptors, which probably explains why it doesn’t have mind-altering effects, unlike THC, which positively regulates the CB1 receptor. That’s why most marijuana grown for recreational purposes are typically very low in CBD and high in THC.
Our CBD Based Products
CBD Oil Balm
Extra Strength CBD Balm. Infused with concentrated Gold Formula CBD, our Extra Strength Balm contains double the amount of CBD. Plus CBD Oil™ Extra Strength Balm contains more of what the skin craves. Extra strength CBD Balm absorbs quickly into the skin, providing a soothing and moisturizing experience.
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CBD Oil Capsules
Plus CBD Oil™ is gluten-free, non-GMO and the most consistently pure product family in the industry, Harness your human potential with Plus CBD Oil.
Consumed by adults all around the world, Plus CBD Oil™ is trusted to deliver the most pure, consistent and traceable cannabinoids in North America. With naturally occurring Vitamin E, fatty acids and cannabidiol, Plus CBD Oil™ supports a healthy mind-body balance.
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CBD Oil Drops
Our Plus CBD Oil™ Drops contain a complex phytocannabinoid matrix including cannabidiol (CBD) from agricultural hemp, providing enhancing CBD support using our Gold Formula – our highest concentration of CBD oil.
Our drops are made with our best-selling Gold Formula, Plus CBD Oil drops provide an easy way to enjoy CBD. Available in 1oz and 2oz bottles in peppermint and unflavored tastes, in both 250mg and extra strength 750mg potencies.
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CBD Oil Sprays
Our CBD Oil Spray is the easiest and most flexible option for people who take CBD Oil daily. A good option for people who are new to CBD oil, sprays come in conveniently sized bottles and in three delicious flavors. With naturally occurring Vitamin E, fatty acids and cannabidiol, every Plus CBD Oil™ product offers quality, purity and consistency. Our CBD Oil sprays are made with cannabidiol (CBD) that is derived from naturally grown agricultural hemp.
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8 Proven Benefits of CBD
1. Relieves Pain and Inflammation: Among common CBD benefits, natural pain relief tops the list for many. Evidence suggests that cannabinoids may prove useful in pain modulation by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found that CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other nonpsychoactive components of marijuana may represent a novel class of therapeutic agents for the treatment of chronic pain.
According to a 2007 meta-analysis conducted in Canada, the combination of CBD and THC buccal spray was found to be effective in treating neuropathic pain in multiple sclerosis, which can be debilitating for 50 to 70 percent of MS patients.
2. Has Antipsychotic Effects: Research shows that CBD benefits include producing antipsychotic effects. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal studies. Additionally, studies show that CBD prevents human experimental psychosis and is effective in open case reports and clinical trials in patients with schizophrenia, with a remarkable safety profile.
3. Reduces Anxiety: Studies using animal models of anxiety and involving healthy volunteers clearly suggest an anxiolytic-like effect of CBD. Cannabidiol has shown to reduce anxiety in patients with social anxiety disorder and researchers suggest that it may also be effective for panic disorder, obsessive compulsive disorder, social anxiety disorder and post-traumatic stress disorder.
A 2011 study aimed to compare the effects of a simulation public speaking test on healthy control patients and treatment-native patients with social anxiety disorder. A total of 24 never-treated patients with social anxiety disorder were given either CBD or placebo 1.5 hours before the test. Researchers found that pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alertness in anticipation of their speech. The placebo group presented higher anxiety, cognitive impairment and discomfort.
4. Fights Cancer: Several scientific reports demonstrate that CBD benefits include possessing antiproliferative, pro-apoptotic effects that inhibit cancer cell migration, adhesion and invasion. (9) A 2006 study published in the Journal of Pharmacology and Experimental Therapeutics found for the first time that CBD potently and selectively inhibited the growth of different breast tumor cell lines and exhibited significantly less potency in non-cancer cells.
In 2011, researchers added light on the cellular mechanism through which CBD induces cell death in breast cancer cells. They showed that CBD induced a concentration-dependent cell death of both oestrogen receptor-positive and oestrogen receptor-negative breast cancer cells. They also found that the effective concentrations of CBD in tumor cells have little effect on non-tumorigenic, mammary cells.
CBD behaves as a non-toxic compound and studies show that doses of 700 milligrams per day for 6 weeks did not show any overt toxicity in humans, suggesting that it can be used for prolonged treatment. Not only does the research show that CBD benefits including being effective in fighting breast cancer cells, data also suggests that it can be used to inhibit the invasion of lung and colon cancer, plus it possesses anti-tumor properties in gliomas and has been used to treat leukemia.
5. Relieves Nausea: Cannabis has been used for centuries for the suppression of nausea and vomiting. Research has revealed that among more than 80 cannabinoid compounds found in marijuana, both the intoxicant THC and the non-intoxicant CBD helps to get rid of nausea and vomiting in animal studies. A 2012 study published in the British Journal of Pharmacology found that CBD benefits including possessing anti-nausea and antiemetic effects when it was administered to rats. Researchers found that CBD acts in a diphasic manner, meaning that in low doses it suppresses toxin-induced vomiting, but in high doses it increases nausea or has no effect.
6. May Treat Seizures and Other Neurological Disorders: A 2014 survey conducted by researchers at Stanford University was presented to parents belonging to a Facebook group dedicated to sharing information about the use of cannabidiol-enriched cannabis to treat their child’s seizures. Nineteen responses met the inclusion criteria for the study: a diagnosis of epilepsy and current use of CBD-enriched cannabis. The average number of anti-epileptic drugs tried before using CBD cannabis was 12. Sixteen (84 percent) of the 19 parents reported a reduction in their child’s seizure frequency while taking CBD cannabis. Of these, two (11 percent) reported complete seizure freedom, eight (42 percent) reported a greater than 80 percent reduction in seizure frequency, and six (32 percent) reported a 25–60 percent seizure reduction. Other beneficial effects included increased alertness, better mood and improved sleep; while side effects included drowsiness and fatigue.
Later in 2014, researchers reported on preliminary results of a study involving children with treatment-resistant epilepsies in an expanded access “compassionate use program.” Patients received a purified 98 percent oil-based CBD extract called Epidiolex, which is made by GW Pharmaceuticals. After 3 months of treatment, 39 percent of the 23 patients had more than a 50 percent reduction in seizures, with a 32 percent median reduction. These preliminary results support the animal studies and survey reports that CBD may be a promising treatment for treatment-resistant epilepsy and it is generally well-tolerated in doses up to 25 milligrams per kilogram of body weight.
7. Lowers Incidence of Diabetes A 2006 study found that CBD treatment significantly reduced the incidence of diabetes in non-obese diabetic mice from an incidence of 86 percent in non-treated mice to an incidence of 30 percent in CBD-treated mice. CBD benefits also showed a significant reduction of plasma levels of pro-inflammatory cytokines. A histological examination of the pancreatic islets of the CBD-treated mice revealed significantly reduced insulitis. (16)
In 2013, the American Journal of Medicine published a study that highlighted the impact of marijuana use on glucose, insulin and insulin resistance among U.S. adults. The study included 4,657 adult men and women from the National Health and Nutritional Examination Survey from 2005 to 2010. Of the participants, 579 were current marijuana users and 1,975 were past users. The researchers found that current marijuana use was associated with 16 percent lower fasting insulin levels. They also found significant associations between marijuana use and smaller waist circumferences, a factor connected to the onset of diabetes symptoms.
8. Promotes Cardiovascular Health: A 2013 study published in the British Journal of Clinical Pharmacology reports that CBD protects against the vascular damage caused by a high glucose environment, inflammation or the induction of type 2 diabetes in animal models; plus, CBD proved to reduce the vascular hyperpermeability (which causes leaky gut) associated with such environments.
Frequently Asked Questions
What is Cannabidiol (CBD) Oil?
Cannabidiol is one of the most well-known, non-psychoactive cannabinoids found in the hemp plant. CBD binds to receptors in your immune system, providing a variety of medicinal benefits. It was originally patented by the United States Government in 2003 as a neuroprotectant and antioxidant.
CBD oil is obtained by extracting CBD from the hemp plant using a process in which CO2 is at a low temperature, under high pressure. By doing this, CO2 is captured in a liquid state, drawing out CBD and terpenes from the hemp plant.
What are CBD oil effects?
CBD, along with other cannabinoids, interact with CB1 and CB2 receptors within the human endocannabinoid system to regulate homeostasis. CBD is also known for its ability to influence physiological functions including sleep, mood, memory, pain modulation, immune function, cardiovascular function and inflammatory response.
Why does CBD oil purity matter?
CBD oils are widely available throughout the United States and require no formal FDA approval or ongoing regulation like pharmaceutical products require. Many CBD oil manufacturers may utilize poor quality cannabidiol ingredients, add unnecessary additives to the product and employ subpar extraction and processing practices, all of which could sacrifice the quality and therapeutic potential of the product.
What are CBD oil side effects?
There are no known CBD oil side effects; CBD is well tolerated among patients with a wide variety of health concerns. If a person experiences side effects from CBD oil, it is generally due to impurities in the oil and poor manufacturing processes. This can be avoided by purchasing a high-quality CBD oil from a trusted manufacturer.
Is CBD oil legal?
CBD manufactured from hemp is legal in the United States. The head of the DEA, Chuck Rosenberg, stated that hemp farmers and hemp that is grown in accordance with the US Farm Bill is safe from the DEA. More specifically, American hemp grown in accordance with the US Farm Bill as well as products derived from it, such as hemp CBD oil, hemp CBD isolate, hemp CBD crystals, hemp CBD edibles, hemp CBD water solubles, and any other hemp CBD products, are protected from the DEA.
What are terpenes?
Terpenes are organic, aromatic molecules produced in the resin of the hemp plant along with cannabinoids, and are responsible for its fragrances, flavors, and color. There are more than 100 different terpenes within the hemp plant; their main goals are to protect the plant from predators and attract pollinators.
Terpenes are also found in other living organisms, such as plants, herbs, and fruits, and serve similar protective purposes in each. When terpenes are dried, they are referred to as terpenoids, a name commonly used interchangeably with terpenes.
Why are terpenes important?
Terpenes, like cannabinoids, offer medicinal benefits when extracted from the hemp plant and are thought to have anti-inflammatory and antibacterial properties.
Terpenes bind to cannabinoid receptors in the brain and work synergistically with cannabinoids to mediate stress, mood and the ability to focus.
What is the difference between THC and CBD?
THC and CBD are the two main cannabinoids found in the cannabis plant. The main difference between the two cannabinoids is that THC is psychoactive and responsible for the “high” feeling associated with smoking marijuana, while CBD is not.
Psychoactivity occurs because THC is a CB1 receptor agonist. When THC is introduced to the body, it binds well with CB1 receptors in the brain and mimics a cannabinoid produced naturally by the body called anandamide, known as the bliss cannabinoid. Anandamide is known to increase appetite and mood and is involved in functions like memory and motivation.
Conversely, CBD does not bind well with CB1 receptors and is considered a CB1 antagonist, actually working to suppress the effects of THC.
Does CBD get you high?
No, CBD does not get you high. In fact, CBD works to counteract the psychoactive effects of THC, the cannabinoid responsible for the high feeling. CBD oil is non-addictive and you cannot overdose as a result of taking the oil.
Can you fail a drug test due to CBD?
Marijuana drug tests collect urine samples to test them for THC. If the product you consume contains only CBD, then it is unlikely you would test positive for marijuana. Even trace amounts of THC in a CBD product are unable to trigger a positive drug test result because the drug tests set thresholds for THC around 50ng/mL.
What is the proper dosage for CBD oil?
CBD is measured in milligrams (MG) for quantitative purposes. Research is showing that about 5-10MG daily is a good intake of CBD to activate your CBD receptors. If someone is suffering from a more serious illness, then 20-40MG daily is recommended. Your healthcare provider can help establish a dose which will work best for you.
How long does it take for CBD oil to work?
Depending on the potency of the CBD oil, the time it takes to become effective may vary. Many patients report anywhere from 20 minutes to 1 hour for the CBD oil to take effect. Because CBD does not produce psychoactive results, patients may not notice the exact moment where a change in symptoms occurs, unless its use is in pain relief.
What is the difference between hemp and marijuana?
Agricultrial hemp has tall, bamboo like, thick stocks, very thin leaves, and little to no flowers. Defined as a cannabis plant containing less than 0.3% THC, hemp is grown mainly to make textiles, food, oils and does not get you “high”.
Disclaimer: CBD Oil is not intended for use under the age of 18. Do not take if you are pregnant or lactating. Consult your physician before use if you have a medical condition or are taking any medication. Do not exceed recommended serving size.