What is the difference between THC and CBD?

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THC and CBD are the two main cannabinoids found in the cannabis plant. The main difference between the two cannabinoids is that THC is psychoactive and responsible for the “high” feeling associated with smoking marijuana, while CBD is not.
Psychoactivity occurs because THC is a CB1 receptor agonist. When THC is introduced to the body, it binds well with CB1 receptors in the brain and mimics a cannabinoid produced naturally by the body called anandamide, known as the bliss cannabinoid. Anandamide is known to increase appetite and mood and is involved in functions like memory and motivation.
Conversely, CBD does not bind well with CB1 receptors and is considered a CB1 antagonist, actually working to suppress the effects of THC.